Regenerative treatment can be the best natural treatment for severe chronic lower back pain and knee arthritis.
Regenerative treatment includes regenerative cell therapy and platelet-rich plasma (P.R.P.) therapy. This minimally invasive therapy can heal and restore the damaged tissues quickly and naturally. It is only your cells that are used to amplify the cells at the damaged site, heal the damaged tissues, and regenerate newer tissues. Hence, there is no risk of rejection or allergy. Though complete regeneration takes some time, patients will notice significant changes within a few weeks. Hence, regenerative therapy is the best alternative to treat severe chronic lower back pain and knee arthritis.
Moreover, there is ample evidence to support this treatment.
A research study published in the journal Arthroscopy revealed that P.R.P. injections were significantly more effective than hyaluronic acid injections by providing long term pain relief with improved joint function. Hyaluronic acid can only lubricate the knee joint, but it cannot treat cartilage loss, unlike P.R.P. therapy [1].
Another scientific study revealed that regenerative cell therapy might provide better pain relief compared to NSAIDs drugs and corticosteroid injections [2].
Compared to corticosteroid injections, P.R.P. therapy provides more long-term relief from joint pain and enhances the quality of life in a shorter duration. People think that P.R.P. treatment is just like cortisone. But it is not in fact. Long-term use of cortisone injections will ultimately suppress the body’s natural healing mechanism and end up with knee replacement surgery. But P.R.P. therapy aims at repairing the injured tissue by stimulating your body’s healing mechanism naturally. Hence, you do not end up with surgery in the later stage [3].
Recently, SVF (Stromal Vascular Fraction) cell therapy in elders with grade 2-4 degenerative knee osteoarthritis is safe, rapid, and effective with significant improvement in their quality of life [4]. Nevertheless, the use of BMAC (Bone Marrow Aspirate Concentrate) therapy is equally safe and beneficial [5].
References
Dai, WL; Zhou, AG; Zhang, H; et. al. Efficacy of Platelet-Rich Plasma in the treatment of Knee Osteoarthritis: A Meta-analysis of Randomized Controlled Trials. Arthroscopy; 12/22/2016.
Iijima, H., Isho, T., Kuroki, H., Takahashi, M., & Aoyama, T. (2018). Effectiveness of mesenchymal stem cells for treating patients with knee osteoarthritis: a meta-analysis toward the establishment of effective regenerative rehabilitation. N.P.J. Regenerative medicine, 3(1), 1-13.Forogh B, Mianehsaz E, Shoaee S, Ahadi T, Raissi GR, Sajadi S. Effect of single injection of Platelet-Rich Plasma in comparison with corticosteroid on knee osteoarthritis: a double-blind randomized clinical trial. J Sports Med Phys Fitness. 2015 Jul 14. [Google Scholar]
Michalek J, Vrablikova A, Darinskas A, et al. Stromal vascular fraction cell therapy for osteoarthritis in elderly: Multicenter case-control study. J Clin Orthop Trauma. 2019;10(1):76‐80. doi:10.1016/j.jcot.2018.11.010
Di Matteo B, Vandenbulcke F, Vitale ND, et al. Minimally Manipulated Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Systematic Review of Clinical Evidence. Stem Cells Int. 2019;2019:1735242. Published 2019 Aug 14. doi:10.1155/2019/1735242
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